Is Sunshine Good Medicine for ADHD?

New research suggest a surprising connection
Reported By: More Sunshine Tied to Fewer Cases of ADHD – Psych Central News
psychcentral.com

A study published in the journal Biological Psychiatry reveals that sunnier parts of the world have fewer children with ADHD. Sunshine was measured as ‘solar intensity.’

This study echoes previous research that found that outdoor activities, especially those in a green outdoor setting, mitigate ADHD symptoms.

While a significant link was found, the researchers noted that other unknown factors could contribute to lower cases of ADHD in sunny spots. They cited that some sunny states (Florida for example) don’t have low rates of ADHD.

Read the entire article here: http://psychcentral.com/news/2013/03/31/more-sunshine-tied-to-fewer-cases-of-adhd/53226.html

» More Sunshine Tied to Fewer Cases of ADHD – Psych Central News
psychcentral.com
Fewer children have attention-deficit hyperactivity disorder (ADHD) where sunshine is plentiful, according to new research published in the journal Biological

What You Should Know About Supplements (part 2)

Are Cheerios medicine?

As stated in the Part 1 of this series, senator Durbin is leaning toward labeling all supplements as drugs. Need vitamin C? Calcium? You may have to get a prescription from your doctor if his bills pass. Stay informed.

Letter from the Food and Drug Administration.
Did you know the FDA went after General Mills for saying their Cheerios were heart healthy? See the full letter here: http://www.fda.gov/iceci/enforcementactions/warningletters/ucm162943.htm

As ridiculous as this seems (no one would overdose after eating even an entire box of Cheerios), the FDA wants you to know that making claims about cholesterol reduction would classify Cheerios as medicine even though clinical studies have shown it’s possible to reduce cholesterol after eating Cheerios due to the water soluble fiber contained in them.

The same nonsense occurred with POM Wonderful 100% Pomegranate Juice.

Supplements that make any medical claims would also be considered medicines. This is why you see this statement so frequently: “XXXX is not intended to treat or cure any disease. The claims made for XXXX have not be evaluated by the Food and Drug Administration.”

As stated in the Part 1 of this series, senator Durbin is leaning toward labeling all supplements as drugs. Need vitamin C? Calcium? You may have to get a prescription from your doctor if his bills pass. Stay informed.
General Mills, Inc. 5/5/09
www.fda.gov
Promotional Claims False & Misleading/Misbranded

The Top Vitamins, Supplements, and Foods for Your ADHD Child

http://www.additudemag.com/adhdblogs/11/9970.html

A FREE Webinar from ADDitude magazine

This is a great opportunity to learn how diet can make changes for your ADHD child.

http://www.additudemag.com/adhdblogs/11/9970.html

ADHD EXPERT WEBINAR: Best Bites — Top Nutritional Choices for Your ADHD Child
www.additudemag.com
Join us for the expert webinar hosted by Sandy Newmark, M.D., on Monday, March 18, 2013 at 1 PM EST. ADHD symptoms, diagnosis, and treatment information for adults.

ADHD and Smoking Later in Life

ADHD and Smoking Later in Life
Is there a connection?
Article published in the journal Archives of Disease in Childhood.
New research published online in the journal Archives of Disease in Childhood (Oct. 29) says that childhood ADHD may increase the likelihood of smoking later in life.

The researchers examined blood samples from 450 ADHD children aged 6 to 12 years, their siblings, and parents. The samples were tested for genetic variations strongly associated with smoking attributes. These included:

1. The number of cigarettes smoked every day.
2. Starting smoking.
3. Quitting smoking.
4. Times of smoking.

The researchers also asked the mothers about their smoking habits during pregnancy. The data indicated that ADHD people are more likely to start smoking early and to smoke twice as much as those without ADHD.

This research is similar to research indicating a relationship between ADHD and drug use in later life.

Although the study found an association between the genetic variant and ADHD and smoking behaviors, it did not prove a cause-and-effect relationship so further research is necessary.

However, even without a cause-effect relationship, the data need to be heeded. Start early prevention.

Prenatal Exposure to Mercury May Be Linked to ADHD

Mothers beware of your diet

We’re all concerned about contaminants in our environment. We worry about drinking clean water, breathing clean air, and eating non-toxic food. A recent study published online Oct. 8 in Archives of Pediatrics & Adolescent Medicine reveals another possible concern: mercury hidden in fish. The study links mercury exposure in expectant mothers to ADHD symptoms in their children at the age of 8. Mercury is known to affect the human nervous system.

As with other studies of mercury and its possible link to ADHD, the current study “adds to concerns about mercury consumption and to evidence about the benefits of fish consumption,” said Dr. Susan Korrick. Korrick is the study’s co-author and an assistant professor of medicine at Harvard Medical School and Brigham and Women’s Hospital in Boston.  Korrik’s team found that more mercury exposure leads to a higher incidence of ADHD symptoms. However, more fish consumption — the main source of mercury exposure — leads to a decreased risk.

“How much fish you eat is not equivalent to how much mercury you are exposed to,” said Dr. Korrick. “I think the public health conclusion that I would come to is that one can benefit from fish consumption, but it’s important to try to consume fish that are low in mercury.” Fish high in mercury include swordfish,shark, and fresh tuna. Fish with lower levels of mercury include salmon, haddock, shrimp, and cod.

Korrick and her reviewed data on children at age 8 from the New Bedford, Mass., area who were born between 1993 and 1998. New Bedford is on Massachusetts’ coast and is a fishing community where fish consumption is popular. Fish consumption is a primary source of mercury. Korrick’s team investigated whether greater mercury exposure before birth, prenatal exposure via mothers’ wombs, might lead to more behavioral problems in kids later in life.

The researchers tested the children and evaluated teacher reports. The researchers found that some children of mothers who had the highest levels of mercury before birth were 40 percent to 70 percent more likely to have the behavioral problems.

There are flaws to the research because of its design. It doesn’t prove that mercury is directly responsible for the behavioral problems or ADHD although prior studies have found links. Also, children in the study were not actually diagnosed with ADHD because the study only looked at ADHD symptoms. Better to be safe than sorry regarding mercury consumption.

ADHD — It’s all in the hands

Can certain hand movements reveal ADHD?

Two studies, both funded by the U.S. National Institutes of Health and published in the Feb. 15 issue of the journal Neurology, reveal that ADHD children have a greater amount of unintentional hand movement than children not labeled ADHD.

Researchers from Cincinnati Children’s Hospital Medical Center and the Kennedy Krieger Institute in Baltimore performed joint research using sequential finger-tapping experiments on children with ADHD. The researchers found that ADHD children exhibited more than twice the amount of unintentional movements than typical children on one of the two tests used.

Additionally, the researchers measured cortical inhibition with magnetic pulses (transcranial magnetic stimulation or TMS) and compared the results to children without ADHD.

Let’s do a little brain anatomy here to make things clearer. The cortex is a layer or sheet of neural tissue that is outermost to the cerebrum. The cortex is responsible for attention, memory, consciousness, thinking, perceptual awareness, and language. The motor cortex is a term that describes regions of the cerebral cortex. The motor cortex plays a key role in the planning, control, and execution of voluntary motor functions (like hand movement).

Cortical inhibition is a term used to describe the cortex’s ability to control these functions.  By using magnetic pulses directed across the cortex, the researchers discovered that children with ADHD were less able to inhibit their hand movements than children without ADHD. ADHD children presented unintentional hand movements about 40 percent more of the time than children without ADHD.

“We now have a real, quantifiable measure of a problem with controlling behavior in these children,” said Dr. Stewart Mostofsky, primary author of the study performed at the Kennedy Krieger Institute.

“From a clinical standpoint, the critical issue is … they do have differences with these aspects of normal motor control,” Mostofsky said. “We have to recognize that and account for that in considering how to work with children with ADHD.”

Notably, ADHD children that presented the greatest inability to inhibit their hand movement usually received more severe parental reports of hyperactivity and impulsivity.

The question obviously missing is, “What is the significance of these two studies?” They do not provide any direct applications for either diagnosis or treatment of ADHD. Could any parent with an ADHD child tell the researchers that their ADHD child could not control himself like other children his age? The answer is likely a resounding, YES!

The studies do identify patterns of inhibition control. This has been documented in previous studies and is a known factor in ADHD. Could the researchers develop a diagnostic tool based on inhibition control? Yes. As a matter of fact, this type of measurement is commonly obtained in a Computerized Performance Test or “CPT.”

The CPT typically flashes a letter, number, or symbol on a computer screen. The student is tasked to press the space bar or mouse when a preselected number, letter, or symbol appears on the screen. The computer will measure how many times the student clicks correctly, incorrectly, unnecessarily, or impulsively. A wide variety of data are obtained from a CPT. Yet they can only be part of a comprehensive evaluation for evidence of ADHD as so many variables are involved that may mimic ADHD.

So, while studies like the finger tapping study are interesting, they do not provide significant insight into the field nor do they provide basis for a single method of diagnosis. One may wonder why we fund such studies given what is already known in the field.

Diet and ADHD Symptoms

The February 5, 2011 issue of The Lancet reports that researchers in the Netherlands and Belgium were able to significantly reduce ADHD symptoms through restrictive dietary measures.

This theory has long been advocated by such notable groups as The Feingold Association (http://www.feingold.org/). However, their studies have been limited to smaller groups and anecdotal evidence. While their findings have been compelling, medical doctors and adversarial attacks by the processed food industry quashed overall acceptance of dietary restriction. The NIMH give only limited credence to the theory.

Feingold and other advocates of the restrictive diet have suggested that the introduction of food additives can affect the human immune system sometimes causing reactions like hyperactivity, inattention, and even eczema, asthma and gastrointestinal problems. In light of research about food colorings and hyperactivity, the British have taken steps to eliminate certain preservatives and food dyes from their food supply.

The study published in the Lancet was funded by Foundation of Child and Behaviour, Foundation Nuts Ohra, Foundation for Children’s Welfare Stamps Netherlands, and the KF Hein Foundation.  The researchers placed  100 children from Belgium and the Netherlands into two groups: one that received the restrictive diet and the other that only received advice on healthy eating habits. The group that received only advice on healthy eating was the control group. All of the children had been diagnosed with ADHD and were between the ages of 4 and 8.

The children were placed on the restrictive diet for a period of five weeks. They were allowed to eat only rice, meat, vegetables, pears and water. Later, the children were allowed to additionally consume potatoes, fruits and wheat. The researchers assessed ADHD symptoms during this period.

Over the course of the next four weeks, researchers reintroduced processed foods into the restricted diet group. The researchers selected foods that were previously considered to negatively affect body or immune responses.

Nine children withdrew from the restrictive diet group. Attrition in all studies is common. Of the forty-one children who completed the restrictive diet program, 78 percent had a reduction in their ADHD symptoms, compared with no improvement in the controls. Assessment was performed using an ADHD symptom scale that ranges from 0 to 72 points. Higher scores in the scale indicate more severe symptoms. The average reduction was 24 points, a significant reduction.

Thirty children who demonstrated decreased ADHD symptoms resulting from the restrictive diet were selected for reintroduction of foods outside the restrictive diet. This was deemed the ‘challenge test.’ Nineteen of the thirty children had a relapse in symptoms on the challenge test. Sensitivity to foods thought to produce high immune response didn’t seem to produce any greater negative effects than foods thought to produce lower immune response.

Limitations of the study include restriction to ADHD; it cannot be discerned whether it would apply to ADD. Secondly, not all children responded to the restrictive diet. Of those who did respond, responses to foods seemed to be equal no matter what processed food was introduced back into the diet. Additionally, under this research design, it was not possible to have a blind control; parents knew what group their child was in. If they also knew the expected outcome of the study, it might have influenced the outcome.

On the practical side, the restrictive diet is very difficult to follow consistently. However, if your child seems to respond well when you remove certain processed foods, this research seems to support your observation although the certainty about diet and ADHD symptoms has not been clearly established by this study.

Texting and ADHD

How much has information and communication technology (ICT) affected our lives? Researchers say that the average teenager sends a total of over 3,400 electronic [text] messages every month or surfs the Internet at bedtime. Could texting and bedtime web time influence the severity of your child’s ADHD symptoms?

In a study by the JFK Medical Center in Edison, New Jersey, and presented at the 76th annual meeting of the American College of Chest Physicians (ACCP), lead author Dr Peter G. Polos and his team found that more than half of these bedtime kiddy texters or web surfers are not only prone to have problems falling asleep, but experience mood, behavior and cognitive problems during the day.

“It is significant that these children are engaging in stimulating activity when they should be in an environment to promote sleep,” says Polos.

Polos’ team analyzed questionnaire responses from 40 children and young adults aged between 8 and 22. This is a small group and the results must be considered preliminary. However, the researchers found that those who used electronic technology at bedtime (texting, game playing, email, surfing, etc.) also experienced sleep-related problems such as excessive movements, leg pain and insomnia, and also had a “high rate of daytime problems, which can include attention deficit hyperactivity disorder [ADHD], anxiety, depression, and learning difficulties,” said Polos.

According to Medical News Today (www.medicalnewstoday.com), the analysis of the questionnaire data showed that:

* 77.5 per cent of the participants had persistent problems falling asleep.

* On average, participants were woken once per night by an ICT device.

* On average, a participant sent 33.5 emails or texts per night when they were supposed to be asleep; and the average number of people texted each night was 3.7.

* The average number of messages sent via ICT per person per month at sleep time was 3,404 and occurred over periods ranging from 10 minutes to 4 hours after bedtime.

* Among the adolescent participants, the older they were, the later they went to bed, and the more time they spent with their ICT devices at bedtime.

* Boys were more likely to use ICT to surf the net and play online games, while girls were more likely to text and make cell phone calls.

* High rates of cognitive and mood problems during the day were linked with sleep time related use of ICT, including ADHD, anxiety, depression, and learning difficulties.

* There were also higher rates of nighttime problems such as excessive movements, leg pain and insomnia.

Polos and colleagues concluded that use of ICT at bedtime may have “an adverse impact on sleep hygiene and daytime function which may be significant”, and that questions about this should be included in routine evaluations of patients reporting problems sleeping.

“These data suggest that further studies are needed to evaluate the short and long term consequences of STRICT on sleep,” they wrote.

Polos explained that “sleep is largely habitual in nature”, and if “children begin this type of behavior, they may set themselves up for the need for external stimulation before sleep later in life”.

This could lead to problems like difficulty falling asleep, not having enough sleep, and feeling sleepy during the day, he said adding that:

“More research is needed to determine all of the short- and long-term consequences.”

Many parents know that healthy sleep habits are especially important to ensure progress at school and healthy development, and are concerned about how best to handle the growing problem of ICT devices in the bedroom.

Polos said that using cell phones or computers, to talk, text, surf the net, or play games, is “more addictive, seductive, and interactive than passively watching television,” because of the graphics, rapid responses and interactivity.

“The sooner parents establish appropriate times for children to use this technology, the better,” he urged, adding that perhaps they should also “move key items, such as computers, from a child’s bedroom into a common area”.

Dr David Gutterman, President of the American College of Chest Physicians said concern about insomnia and other sleep disorders in children is growing and that “research shows that the problem is increasing, so it is more important than ever for physicians to ask questions about technology use when evaluating children for sleep issues”.

ADHD’s Genetic Link

What causes attention-deficit hyperactivity disorder – ADHD? Research in the English medical journal, The Lancet, says it’s not too much sugar, bad diet, or poor parenting. Professor Anita Thapar, lead author of the study, says it’s likely genetic.

Thapar and her group of scientists at Cardiff University in Wales compared 366 children with ADHD to 1,047 kids without ADHD. In particular, the researchers examined differences in the children’s DNA. They found that kids with ADHD were more likely to have small segments of DNA that were duplicates or missing (copy number variants or CNVs — either a deletion or duplication of genetic material).

“We hope that these findings will help overcome the stigma associated with ADHD,” Professor Anita Thapar, the study’s lead author, said in a written statement. “Too often, people dismiss ADHD as being down to bad parenting or poor diet. As a clinician, it was clear to me that this was unlikely to be the case. Now we can say with confidence that ADHD is a genetic disease and that the brains of children with this condition develop differently to those of other children.”

While being media friendly, Thapar’s last statement is a stretch in relation to her research. People and the media love statements that provide seemingly conclusive answers.

Let’s go beyond the media hype that says this research concludes there is a definite genetic link. The researchers really only say there seems to be a possible “genetic link.”  However, their research did not conclude that it is purely or even primarily genetic. What they truly are saying is that this study is evidence that ADHD is not purely social.

The authors conclude:

“Our findings provide genetic evidence of an increased rate of large CNVs in individuals with ADHD and suggest that ADHD is not purely a social construct.”

This is logical because only 15% of the research subjects with ADHD demonstrated increased CNVs. So is it safe to conclude that genetic makeup may contribute, at least in some particular cases, to ADHD? Yes, but to be clear,  this research did not conclude that it is entirely genetically based and was only partially genetically based in a small segment of their study population. This is very similar to other genetic research.

Why is it, if ADHD is genetically based, at least in part, that 30% don’t have it as adults when diagnosed as a child? What happened? Where did it go? This is what is most  important to parents and professionals.

Epigenetic theory, now being widely embraced by the scientific community, maintains that human development  includes both genetic origins of behavior and the direct influence that environmental forces have on the expression of those genes (nature/nurture). Epigenetic theory regards human development as a dynamic interaction between these two influences.

Simply put, how our genes express themselves is greatly impacted by environment. This is likely why, over time, 30% of children don’t display symptoms as adults. The brain changes, rewires, or (a radical version of epigenetic theory) their genes change.

Do tools exist to do this? Yes. See www.playattention.com.

If I may quote Dr. Theodore Dalrymple, “What seems to have happened is that parents have lost the awareness that they had for decades – if not for centuries – that concentration and self-discipline do not come naturally to children, and have to be taught (as well, sometimes, as enforced).”

Training the ADHD Brain

For years, we at Play Attention, have trained thousands and thousands of people to better pay attention, learn the cognitive skills they need to succeed, and change their behavior. Our results have spoken clearly for us since 1994. Now science is catching up.

Two recent distinct studies validate the brain’s ability to change. While a vast plethora of research confirms these studies’ findings, they are noteworthy. The first study demonstrates the efficacy of skill training, and the second demonstrates how teaching skills rewires the living brain.

The first study, published in the August 25 Journal of the American Medical Association, was performed by researchers from Massachusetts General Hospital (MGH). They utilized cognitive behavioral therapy as a direct intervention for ADHD adults. Cognitive therapy teaches skills for managing life challenges.

The researchers at  MGH found that while medications were the first line of treatment, many patients still persist with underlying symptoms.  While previous studies on cognitive behavioral therapy for ADHD were small and short term, the researchers at MGH claim their study to be the first to conduct full-scale randomized, controlled trial of the efficiency of an individually-delivered, non-medication treatment of ADHD among adults.

“Medications are very effective in ‘turning down the volume’ on ADHD symptoms, but they do not teach people skills,” commented Steven Safren, PhD, ABPP, director of Behavioral Medicine in the MGH Department of Psychiatry, who led the study. “This study shows that a skills-based approach can help patients learn how to cope with their attention problems and better manage this significant and impairing disorder.”

“Sessions were designed specifically to meet the needs of ADHD patients and included things like starting and maintaining calendar and task list systems, breaking large tasks into manageable steps, and shaping tasks to be as long as your attention span will permit,” commented Safren, an associate professor of Psychology in the Harvard Medical School Department of Psychiatry. “The treatment is half like taking a course and half like being in traditional psychotherapy.”

Like Play Attention has been doing since 1994, the researchers provided training sessions mainly that included skills training in filtering of distractions, organization, problem solving, and planning.

Safren’s group receiving cognitive and behavioral training demonstrated advanced control of their symptoms over their control group.  This benefit had persisted when measured three and nine months after the training.

The second study, published in The Journal of Neuroscience (August 25, 2010, 30 34 11493-11500 doi 10.1523 JNEUROSCI.1550-10.2010), examined the brains of rats when they learned to control their impulses.  The researchers documented synaptic changes in the medial prefrontal cortex. They concluded that the rat’s brains rewired themselves to produce the impulse controls necessary to be successful in the tasks the scientists had established for them.

Other past studies have confirmed that the brain will rewire to make changes for skills, impulse control, organization, etc. We’re glad that science is catching up to an learning process that we’ve done at Play Attention for sixteen years now.  That’s beyond cutting edge; it’s leading the way for others.