Sleep Disorders & ADHD

It’s suspected that nearly 25% of all cases identified as attention deficit hyperactivity disorder (ADHD) are not really ADHD at all, but are symptoms related to sleep disorders.

One of the leaders in this research is University of Michigan professor Ronald Chervin.  Chervin theorizes that very important brain development is done during sleep. Among other things, this includes the ability to regulate emotion and processing. So, if a child has chronic sleep problems, brain development may be impaired. Chervin also suspects that the brain does not receive enough oxygen if the child snores which further inhibits development.  According to Chervin’s research, children who snore are more likely to have ADHD.

He likens the ADHD-sleep connection to a child who doesn’t get a nap; he becomes restless, irritable, and acts out.

Chervin developed his theory based on a sleep/behavior survey of the parents of 866 children.  Chervin’s data exposed a sleep disorder -behavior relationship.  It was only logical to conclude that if the sleep disorder could be corrected, the ADHD symptoms would be extinguished.

According to Newsweek: “To test this theory, Chervin then studied 79 kids (5 to13 years old) who were about to have an adenotonsillectomy. Prior to the surgery, 22 of the 79 were categorized as having ADHD, based on standard measures for such a diagnosis. One year later,  Chervin’s team tracked down the kids for a follow-up. Of the 22 identified as having ADHD, 11 kids no longer qualified as having the disorder.”

Two problems lingered: 1) New cases of ADHD cropped up and 2) 50% of the surgical patients received no benefit at all.

Before you go and get your child’s tonsils and adenoids out, let’s discuss the distinct problems in the logic associated with this research.

First, we have a problem of antecedence; does ADHD exist because of sleep problems? or does the sleep problem exist because of  ADHD? That relationship cannot be clearly identified and is a confounding problem.

Secondly, new cases of ADHD appeared and others did not benefit at all from the surgery. This would lead one to think that the outcomes may not be related at all to the procedure.

I’m reminded of an old story about researchers who taught a frog to jump upon saying, “Jump!” Many weeks were spent training the frog.  The researchers were quite happy that they had proved the frog could hear and could respond to the human voice. One of the researchers  decided they should amputate the frogs hind legs. After carefully surgically removing the frog’s legs and rehabilitating the poor frog, the researchers stood in front of the frog and yelled, “Jump!” When the frog did not respond, they all heartily nodded in agreement that the frog’s hearing was severely impaired by the removal of his hind legs.

There is little doubt that sleep problems affect brain development. Past studies have demonstrated that preschoolers with a sleep disorder are twice as prone to substance abuse by early adolescence and more likely to suffer from anxiety in their 20s. Even the American Academy of Pediatrics concurs that sleep problems are not benign.

However, before we undertake invasive, painful surgery as an option, far more research should be performed to absolutely indicate a direct correlation. One currently does not exist and other options should be explored. playing241

It has become obvious that adequate, restful, uninterrupted sleep is essential to our personal well being. Abnormal sleep patterns may result in behaviors that can be easily confused with ADHD.

If your child has a sleep problem, taking them to a sleep specialist may help. Getting adequate exercise, providing a consistent sleep routine/schedule, reducing stress,  and eating a proper diet may also assist in getting better sleep and better behavior.

 

  • Chervin RD, Arcbold KH, Dillon JE, et al. Inattention, hyperactivity and symptoms of sleep disordered breathing. Pediatrics. 2002;109:449-456
  • Chervin RD, Dillon JE, Bassett C, et al. Symptoms of sleep disorders, inattention and hyperactivity in children. Sleep. 1997;20:1185-1192
  • Chervin, RD, Rusicka DL, Giordani BJ, et al. Sleep disordered breathing, behavior and cognition in children before and after adenotonsillectomy. Pediatrics. 2006;117:e769-e778
  • Cortese S, Konofal E, Lecendreux M, et al. Restless leg syndrome and attention deficit/hyperactivity disorder: a review of the literature. Sleep. 2005;28:1007-1013
  • Cortese S, Konofal E, Yateman N,et al. Sleep and alertness in children with attention deficit hyperactivity disorder: a systematic review of the literature. Sleep. 2006;29:504-511
  • Harnish MJ, Boyer S, Kukas L, Bowles AM, et al. The relationship between sleep disorders and attention deficit hyperactivity disorder (ADHD): objective findings. Sleep. 2001;24:A14.
  • Owens JA. The ADHD and sleep conundrum: a review. Journal of Developmental and Behavioral Pediatrics. 2005;26:312-322.

ADHD & Fetal Development

 

Obviously, being pregnant can be stressful in itself, but current research shows that stress can affect fetal development which may lead to long-term problems including ADHD.

Dr. Vivette Glover of Imperial College London, surveyed pregnant women at her hospital. Of these, nearly one quarter felt anxious and depressed due to stressors including work, money, arguing with spouse, and moving to accommodate a larger family. When compared to their non-stressed counterparts in this research, the babies of the stressed mother had lower birth weight, lower IQ, slower cognitive development, and more anxiety. Lower birth weight has been an indicator for coronary heart disease in later life.

In 2007, research in the Journal of the American Academy of Child and Adolescent Psychiatry indicated that being stressed during pregnancy is as detrimental for the baby’s development as smoking or being obese. Glover’s research reveals why and how this happens: stress produces the hormone cortisol. An abundance of stress can actually diminish the barrier enzyme that inhibits cortisol from reaching the fetus. Costisol impacts fetal brain development.

According to Glover, “People used to think that if something was congenital, apparent at birth, it had to be genetic. In fact it can be an in-vitro reaction of genes and environment.”

Glover also contends that her research shows stress greatly increases the likelihood of a child having ADHD (attention-deficit hyperactivity disorder), cognitive delay, autism , anxiety and depression. 

Glover’s research reinforces previous data from the UK where stress was shown to increase the risk for development of ADHD. In that research, the women who experienced the most stress doubled the chances of developing ADHD.

“The organs are forming during the first trimester of pregnancy, but the brain is developing all the way through,” Glover explains. “The organs are sensitive while they are forming and, once formed, they are harder to change.”

“In evolutionary terms, stress perhaps prepares the child for survival in a stressful environment. If a child is anxious and has attention deficiency, it will be very alert to danger. This may once have been adaptive, beneficial for the child, but it isn’t any more,” Glover says.

Significantly, Glover’s research implies that the changes may be on a genetic level so that it may be passed on generation to generation.

Therefore, it’s important to realize that taking care oshutterstock_3753070f ourselves during pregnancy is more important now than ever. Small efforts like seeking health services early, meditating, eating a balanced diet, taking pre-natal vitamins, and laughing are good practices.

Minimizing stress by maintaining a consistent schedule both at work and at home is a good idea.

 

Meditation & ADHD

Sunset & Sky 098 Researchers, Dr. Zylowska, et al from the University of California-Los Angeles conducted a feasibility study of an 8-week mindfulness training program for adults and adolescents with ADHD. Their report was published in The Journal of Attention Disorders (2008 May;11(6):737-46. Epub 2007 Nov 19).

The researchers sought to inquire whether mindfulness meditation could improve attention, reduce stress, and improve mood. The researchers recruited 34 adults and 8 adolescents. Study participants were given a weekly training session. They were also required to practice daily starting with 5 minutes of meditation per day and gradually increasing to 15 minutes per day.

The majority of participants (after dropouts) reported improvements in self-reported ADHD symptoms. Independent tests on tasks measuring attention and cognitive inhibition also indicated improved symptom outcomes. Improvements in anxiety and depressive symptoms were also observed.

In yet another pilot study conducted by Sarina J. Grosswald, Ed.D., a George Washington University-trained cognitive learning specialist, a group of middle school students with ADHD were required to meditate twice a day in school. After three months, researchers found over 50 percent reduction in stress and anxiety and improvements in ADHD symptoms.

"The effect was much greater than we expected," said Sarina J. Grosswald, Ed.D., a George Washington University-trained cognitive learning specialist and lead researcher on the study. "The children also showed improvements in attention, working memory, organization, and behavior regulation."

Due to the neuroplasticity of the brain, better attention can be attained through meditation. Buddhist monks have been doing it for centuries. This seems to be true of ADHD persons as well. However, it is quite apparent that attention difficulties are just the tip of the ADHD iceberg. Other skills including organization, filtering out distractions, memory, time on-task, motor skills, visual tracking, etc, are typically diminished in ADHD persons. A complete program like Play Attention is required to teach these skills.

As for meditation, it is likely a good supplement to training in the aforementioned skill areas, but given the nature of the cited studies, a controlled clinical study is warranted.

Youth and Video Game Addiction

The journal, Psychological Science (May, 2009 Douglas Gentile. Pathological Video Game Use among Youth 8 to 18: A National Study) sampled youth aged 8 to 18.

Iowa State University Assistant Professor of Psychology, Douglas Gentile, found that 8.5% of the gamers to be pathological players. Gentile bases his statistics on standards established for pathological gambling. So, while parents often cite that their child is ‘addicted’ to video games, Gentile’s standards necessitated that video game play actually caused family, social, school or psychological damage due to video game playing habits.

“What we mean by pathological use is that something someone is doing – in this case, playing video games – is damaging to their functioning,” Gentile said. “It’s not simply doing it a lot. It has to harm functioning in multiple ways.”

On average, the pathological gamers in the study played video games at least 24 hours per week. This is nearly twice as much as non-pathological gamers. Parents of pathological gamers also allowed their children to have video game systems in their bedrooms far more often than non-pathological gamers. 

According to Science Daily, Gentile found that pathological gamers reported having more trouble paying attention in school and thus received poorer grades in school, had more health problems, were more likely to feel “addicted,” and even stole to support their habit.

The study also found that pathological gamers were twice as likely to have been diagnosed with attention problems such as Attention Deficit Disorder or Attention Deficit Hyperactivity Disorder.

“There is still much we do not know,” Gentile said. “We don’t know who’s most at risk, or whether this is part of a pattern of disorders. That’s important because many disorders are co-morbid with others. It may be a symptom of depression, for example. And so we would want to understand that pattern of co-morbidity because that would help us know how to treat it.”

Gentile is continuing his own research, currently conducting both longitudinal and clinical studies to determine risk factors and symptoms found in pathological youth gamers.

It is wise for parents to limit use of video games and TV. Treat them as you would dessert; limited portions used as a reward.

Omega 3 Fatty Acids (Fish Oils) and ADHD

While the topic of nutrition & ADHD is contentious, omega 3s have gained ground in the relief of ADHD symptoms.

Respectable studies from Goteborg University in Sweden, University of South Australia, and Oxford University in the United Kingdom have shown that omega 3 fatty acids have reduced symptoms by as much as 50%. A more recent Norwegian study produced similar results.

In the study performed at the University of South Australia, children were divided randomly into three groups for the first 15 weeks of the study. One group was given a fish oil & primrose oil combination; the second took the same combination plus a multivitamin/mineral supplement, and the third group took a placebo. During the second 15 weeks, the kids on the placebo were given the fish oil & primrose oil combination plus the multivitamin/mineral as well.

While the studies received little press, the results were quite good for the two 30-week fish-oil groups. They demonstrated 40%- 50% improvement in behavior while the 15-week group showed a 30% – 40% percent improvement.

Ritalin and Concerta are the drugs most often prescribed for ADHD. The results actually were far better for fish oil when compared with results of studies of Ritalin and Concerta. Fish oils were more effective.

Let me make it clear that fish oil will not cure ADHD. Could it possibly mitigate symptoms for you? Possibly. According to Dr. Andrew Weil  “Levels of omega-3s in the plasma and red blood cells of children with ADHD are lower than in kids who don’t have the disorder.”

As attention issues are only the tip of the ADHD iceberg, it’s not a good idea to use fish oils as your only intervention. I strongly recommend using Play Attention; a cognitive program to improve attention, memory, visual tracking, time on-task, motor skills, and discriminatory processing.

Marriage with ADHD Children

When it involves ADHD, psychologist William Pelham is one of the most prolific researchers around. Pelham and his colleague Dr. Brain Wymbs published a longitudinally study (Journal of Consulting and Clinical Psychology. Vol 76(5), Oct 2008, 735-744.) that tracked 282 families with and 206 without ADHD children. They found that couples who have a child diagnosed as ADHD are almost twice as likely to divorce or become estranged compared to couples without an ADHD child. A simple dynamic is causal: ADHD children can be stressful for parents thus magnifying conflicts between spouses. ADHD children also have oppositional behaviors which increase stress at home.

“We have known for a long time that kids can be stressful for their parents. What we show is they can be really stressful and can lead to marital dissatisfaction and divorce,” said Pelham, who works at the State University of New York at Buffalo. “What it means is ADHD should not be treated without involving the parents in the treatment.”

The researchers found that parents with ADHD children tended to reach the point of divorce or separation faster than their peers.

Parents of ADHD children are distinctly aware that battles over homework, chores, discipline are key stressors that provide further conflict between spouses. It is understandable that 22.7 percent for parents of kids with ADHD were divorced by the time the children were 8 years old as opposed to only 12.6 percent of the parents of non-ADHD children.

“Parents of children with ADHD report less marital satisfaction, fight more often, and use fewer positive and more negative verbalizations during child-rearing discussions than do parents of children without ADHD especially if the child also has conduct or oppositional problems,” Pelham and Wymbs noted in their paper.

The researchers discovered that regardless of whether parents had manageable or difficult children, if parents had an ADHD child they were three times as likely to be negative toward each other as parents who did not. Stress was up and patience was thin.

Does medicine help? Medicines can alleviate ADHD symptoms, however the researchers found that most meds were given in the daytime to improve school performance and wore off by evening when the children were to do homework and chores.

The Brits have taken the polar opposite approach to children with ADHD. I find it highly logical and practical: except in extreme cases, they advise parents to learn new parenting strategies to change and cope with their ADHD child. This may well curb the incredible divorce rate among ADHD parents as well as greatly improve their child’s future.

Mothering by Ritalin

A recent study by Dr. Andrea Chronis-Tuscano of the University of Maryland published in the Journal of Clinical Psychiatry indicates that mothers taking a long-acting form of Ritalin can become better parents.

I’ll be honest, it’s studies like these that turn my stomach. The University of  Maryland should be ashamed of producing such hogwash.

“Mothers of children with ADHD are at 24-times increased risk of having the disorder themselves, and recent research shows that adult ADHD impairs parenting,” Chronis-Tuscano said in an interview with Reuters Health. “However, no study until this one has examined whether medicating parents for their ADHD improves parenting.”

Tuscano used a small group of 23 mothers who received either Ritalin or a placebo. The study ran only 7 weeks.  Researchers assessed mothers’ ADHD symptoms and its affect on the mothers’ parenting skills. Side effects of medication were studied as well.

The results: Ritalin was better than placebo at improving ADHD symptoms and parenting behaviors. As the researchers increased the mothers’ dosages, the mothers’ inattention and hyperactivity fell. The mothers’ parenting behaviors improved, became more consistent, and they did not subject their children to corporal punishment (spanking) as much.

These results prompted Chronis-Tuscano to say, that there is likely “a need for behavioral interventions that target impairments in parenting among adults with ADHD.”

Studies like these are very frequently funded by the pharmaceutical industry. University professors are under pressure to publish and are quite amenable to studies like these even though it’s little more than propaganda and trash data.

It has been clearly established that low dose stimulant medication produces virtually the same effect in both ADHD and non-ADHD patients: it increases one’s ability to pay attention to boring tasks – ADHD or not. This is why these medications are highly desirable to high school students and college students.

Both the tone and tenor of this type of research leads us to think something new has been discovered, when indeed it has not. It also leads us to believe that we can become better parents if we take a pill. We know from previous research that training parents is the best intervention for ADHD children. This ranks above medication. It is the recommended course of action in the United Kingdom although it has not been adopted in the US yet.

If we have ADHD, are parents, and have kids with ADHD (possibly a genetic link),  we can be taught coping skills, consistent parenting skills, and appropriate disciplinary methods. Is this more difficult than taking a pill that teaches nothing and works only in the short-term? Yes. Is it better in the long run? Yes.

ADHD is Big Business

Generics don’t produce income for the pharma giants. Giant pharma’s manipulation of pricing affects users – perhaps more now that the economy is a mess. It also affects health and health related decisions. Ethically, this is wrong.

Shire hikes Adderall price as rumors fly

Amid new speculation that Pfizer might snag Shire in a buyout deal, the specialty pharma is following through on its strategy to switch patients to its newest ADHD med Vyvanse as blockbuster Adderall XR nears the end of its patent. Shire is hiking the price of Adderall by 20 percent, a boost that confounded analysts expecting a smaller increase.

The idea, of course, is that by making Adderall more expensive, Shire will shine the spotlight on Vyvanse, whose price is rising by a mere 7 percent. Cost-conscious patients will then switch to the cheaper brand, or so the theory goes. Then, firmly entrenched as Vyvanse users, the patients won’t move to generic Adderall when it hits the market.

Analysts apparently expect the switching to stick; Citigroup upgraded Shire stock on the prospect. But with insurers increasingly vigilant about drug prices, generic Adderall might woo away more Vyvanse users than Shire wants to lose. We’ll have to wait and see how that plays out.

In the meantime, though, investors are bidding up Shire stock on fresh rumors that Pfizer is kicking tires there. The U.K. company surfaces as a rumored Pfizer target from time to time, however, so it’s tough to know whether Pfizer is actually looking, or whether the habitual talk simply got stirred up when Pfizer chief Jeff Kindler made his “open to big deals” statement earlier this week.

Pediatricians on ADHD Drug Heart Risk

The American Academy of Pediatrics has issued a new policy contradicting the American Heart Association’s: stance that children prescribed stimulant medication Schedule II drugs should get a heart screening or EKG prior to taking the drugs. The American Heart Association (AHA) cited the fact that approximately 2.5 million children taking these drugs are at risk of elevated blood pressure and increased heart rate.

The FDA recently insisted that a warning be placed on the medication’s labels indicating risks for sudden deaths in patients with heart problems. Approximately 20-30 sudden deaths have been reported related to stimulant medication in the US and Canada.

The longest study on families and their use of medication, the Multi-modal Treatment of ADHD Children (MTA) study also indicated other side-effects including decreased height and weight.

The American Academy of Pediatricians (AAP) has taken the stance that children taking stimulant medication do not need and ECG or EKG (electrocardiogram) tests because the rate of death is very small in respect of the overall number of children taking the medication. The AAP contends that EKGs are expensive [around $100] and could delay access to effective ADHD treatments which “could have serious implications.” The AAP does advocate careful physical examination, and a review of family history of heart problems including sudden death. It does not, however, advocate routine EKGs.

According to the Associated Press, policy co-author Dr. James Perrin, a Massachusetts General Hospital pediatrician said the academy’s policy makes clear that there’s no scientific evidence to support “this fairly dramatic practice change.”

This is a rather disconcerting stance for several reasons. The first reason is that there are no long-term data demonstrating the safety or risks of stimulant medication especially in conjunction with cardiovascular risk. Secondly, according to the AHA, children with heart abnormalities have a higher incidence of ADHD. Third, stimulant medications are known to decrease both height and weight in children.


It’s also perplexing that the APA advocated cholesterol drug treatment for children as young as 8 years old. Given this history, then it is not out of character for the APA to minimize heart risk.  

The War on Video Games and ADHD

Recently, national media have declared war on TV, video games, and various other media.  Supported by a study performed by the National Institutes of Health (“NIH”), the news appears gloomy; these various media cause obesity, declining grades, etc.  I’ve even read some press that they may be related to childhood onset of diabetes (related to lack of exercise) and ADHD!

The NIH’s claims are alarming and necessitate a review of the method they employed to derive the claim they make that 80 percent of the studies reviewed have linked media use to negative health effects. I’ve said this before, when researchers review other researcher’s studies (study of study approach), generalizations are contrived that don’t necessarily convey actuality.  Granted, I’m not an advocate of chronic video game play, overuse of the Internet, TV, cell phone, or anything for that matter. Overuse is over use. Moderation is best. Overuse tends displace other healthier activities like taking walks, interacting with human beings face to face, or reading a good book.  So before chucking your Xbox out the window, let’s examine the flaws in this study a little more closely. Then, let’s discuss what actually is happening with video game use.

The NIH report was sponsored by sponsored by the nonprofit group Common Sense Media.  To be candid, I like this group.  It makes sense. Its mission statement reads:

Common Sense Media is dedicated to improving the media and entertainment lives of kids and families.

We exist because media and entertainment profoundly impact the social, emotional, and physical development of our nation’s children. As a non-partisan, not-for-profit organization, we provide trustworthy information and tools, as well as an independent forum, so that families can have a choice and a voice about the media they consume.

I’ve reviewed many of the 173 studies included in the NIH report. And while the NIH report conveys that media use impacts children’s health negatively, I am unable to find reliable data that justify this huge generalization.  This generalization was derived by lumping together research on movies, video games, cell phone usage, Internet usage, TV, movies, etc.  Unfortunately, when information is not disaggregated, it does not control for the way in which the media was used during the research or particular types of video games, movies, etc. For example, was the Internet use studied used for play, school research, or shopping?  Were the video games educational or entertainment? With the NIH’s method of aggregating data, we’ll never know.  Compounding this is the fact that research available on the impact of media like texting, social websites, etc. is nascent.

As I’ve noted many times before, children with ADHD tend to be pre-wired to concentrate on high stimulation and less able to control concentration on mundane tasks. This is neither a gift nor a blessing.  However, this coincides with the finding that children with ADHD had watched more TV as toddlers. This correlation often generates a great misconception (often propagated by the media) that TV-viewing causes ADHD. It would be more likely that the predication toward high-stimulation makes TV far more attractive to children with ADHD than playing with a stuffed toy or Legos.

The strongest correlations may be made with obesity and sexual behaviors.  Obesity is obvious; sedentary behavior (sitting in front of the TV or computer) would lead to obesity and many other diseases associated with obesity including diabetes.  Sexual behavior is obvious as well.  Watching others perform sexually whether under a mild TV-G rating or explicit pornography on the Internet, does impact the child watching. Most research indicates that children will experiment with intercourse or other sexual behavior in a correlation with their ability to access it via media.  Of course, what is not accounted for is the impact of parental influence (or lack thereof) and media exposure.

I’m frequently asked questions by parents about media and their children.  “Should I let my child play video games?” “How much TV is too much?”

Video games are not created equally. The most popular utilize compelling, sharp video imagery, fantasy, and violent action. I’m afraid the genie is out of the bottle. Whether you’re concerned about TV or video games, it is vital to first screen what your child is watching or playing.  Watching TV with them or watching them play their video games gives you the opportunity to discuss offensive, sexual, or violent material. You may object and censor their use or viewing of this material.

As a parent, you set the example as well. If you are sedentary, your child will likely be sedentary (as well as your pet). Play with your child, take them outdoors.

Treat video games like dessert. Dessert is given as a reward, and it is given in highly limited quantity.

So, even if research says correlations exist, you mustn’t dismiss the impact that you impart as parent. Study of study correlations often result in generalizations which may or may not be significant to your family.  As parent you are the decider – provided that you accept that role and are proactive.